The Doctorate is based on the study of genetic diseases, with specific focus on hereditary, developmental disorders, renal, bone diseases as well as, solid and hematological cancers. Using new methods like the IPS generation, organoids, and gene editing, allow to study the pathogenesis in human cell and animal  models of rare muscular, renal, neuro-developmental and neurodegenerative and bone diseases and to test possible gene therapies based on gene editing and tissue engineering. Second selection notice for admission to the PhD courses of the University of Siena, 38th cycle, a.y. 2022-23 (see Rectoral Decree 2293/2022): For the PhD in Genetics, Oncology and Clinical Medicine  2 scholarships financed on projects financed by the European Union, NextGeneration UE, wit